Assoc. Prof. Kuo-Long Lou

Education

• 1987 Environmental Engineering, National Cheng Kung University/Republic of China (BS)
• 1989 Institute of Biochemistry, National Cheng Kung University/Republic of China (MS)
• 1993 Department of Structural Biology, University of Basel/Biozentrum, Switzerland (MA)

• 1996 Structural Biology, Biozentrum, University of Basel/Switzerland (PhD)

Experience

• 1991-1992 Institute of Biology III, University of Freiburg/Germany (TA)
• 1992-1996 Structural Biology, Biozentrum, University of Basel/Switzerland (TA)
• 1996 Department of Structural Biology, University of Basel/Switzerland Biozentrum (Postdoc)
• 1997-1999 Department of Medical Physiology and Biophysics/Neuroscience Research Group/University of Calgary Faculty of Medicine (Research Associate)
• 1999-2003 Institute of Oral Biology/College of Medicine/National Taiwan University (Assistant Professor)
• 2002 - Institute of Biochemistry and Molecular Biology/College of Medicine/National Taiwan University (Joint Appointment)
• 2008 - Institute of Biotechnology/College of Bioresources and Agriculture/National Taiwan University (Joint Appointment)

2009 - Center / National Taiwan University (Joint Appointment)

• 1991-1992 Institute of Biology III, University of Freiburg/Germany (TA)
• 1992-1996 Structural Biology, Biozentrum, University of Basel/Switzerland (TA)
• 1996 Department of Structural Biology, University of Basel/Switzerland Biozentrum (Postdoc)
• 1997-1999 Department of Medical Physiology and Biophysics/Neuroscience Research Group/University of Calgary Faculty of Medicine (Research Associate)
• 1999-2003 Institute of Oral Biology/College of Medicine/National Taiwan University (Assistant Professor)
• 2002 - Institute of Biochemistry and Molecular Biology/College of Medicine/National Taiwan University (Joint Appointment)
• 2008 - Institute of Biotechnology/College of Bioresources and Agriculture/National Taiwan University (Joint Appointment)
• 2009 - Center / National Taiwan University (Joint Appointment)

1. Lou KL*, Hsieh MH, Chen WJ, Cheng YC, Jian JN, Lee MT, Lin TL, Shiau YS, Liou HH (2017). Hanatoxin inserts into phospholipid membranes without pore formation. Biochim Biophys Acta. 2017 Jan 28. pii: S0005-2736(17)30040-8. doi: 10.1016/j.bbamem.2017.01.032. (SCI, corresponding author)
2. Lee H, Su YL, Huang BS, Hsieh FT, Chang YH, Tzeng SR, Hsu CH, Huang PT, Lou KL, Wang YT and Chow LP (2016). Importance of the C-terminal histidine residues of Helicobacter pylori GroES for Toll-like receptor 4 binding and interleukin-8 cytokine production. Scientific Reports 6. (SCI)
3. Lee CH, Huang PT, Liou HH, Lin MY, Lou KL and Chen CY (2016). Non-basic amino acids in the ROMK1 channels via an appropriate distance modulate PIP2 regulated pH(i)-gating. Biochemical and Biophysical Research Communications 473(1): 303-310. (SCI)
4. Lin CW, Sun MS, Liao MY, Chung CH, Chi YH, Chiou LT, Yu J, Lou KL and Wu HC (2014). Podocalyxin-like 1 promotes invadopodia formation and metastasis through activation of Rac1/Cdc42/cortactin signaling in breast cancer cells. Carcinogenesis 35(11): 2425-2435. (SCI)
5. Wu PH, Lin SK, Lee BS, Kok SH, Wang JH, Hou KL, Yang H, Lai EHH, Wang JS, Hong CY (2012). Epigallocatechin-3-gallate diminishes cytokine-stimulated Cyr61 expression in human osteoblastic cells: a therapeutic potential for arthritis. Rheumatology 51(11):1953-65. (SCI)
6. Ho MH, Chiang CP, Liu YF, Kuo MYP, Lin SK, Lai JY, Lee BS (2011). Highly Efficient Release of Lovastatin from Poly(Lactic-co-Glycolic Acid) Nanoparticles Enhances Bone Repair in Rats. Journal of Orthopaedic Research 29(10):1504-10. (SCI)
7. Lee BS, Huang LC, Hong CY, Wang SG, Hsu WH, Yamauchi Y, Hsieh CJ, Lai JY, Wu KCW (2011). Synthesis of metal ion-histidine complex functionalized mesoporous silica nanocatalysts for enhanced light-free tooth bleaching. Acta Biomaterialia 7(5):2276-84. (SCI)
8. Lee BS, Wang CY, Fang YY, Hsieh KH, Lin CP (2011). A Novel Urethane Acrylate-based Root Canal Sealer with Improved Degree of Conversion, Cytotoxicity, Bond Strengths, Solubility, and Dimensional Stability. Journal of Endodontics 37(2):246-49. (SCI)
9. Yeh ST, Wang HT, Liao HY, Su SL, Chang CC, Kao HC, Lee BS (2011). The roughness, microhardness, and surface analysis of nanocomposites after application of topical fluoride gels. Dental Materials 27(2):187-96. (SCI)